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It seems to me that the latest version of Hamachi i.e v2.0.3.89 update breaks UPnP on Windows 7 x64. It is seriously unbelievable. When I was using the Windows XP Pro. SP3 32bit, I didn’t see any kind of issues like that before. The problem is if Hamachi is enabled at start up to run, then it obviously going to break UPnP on Windows 7 x64. If the Hamachi2 GUI won’t start then it won’t affect the UPnP, works fine. The issue started only after the automat update of Hamachi2
I have a pretty good work-around for your issue. The solution is, you need to use the built-in Windows Task Scheduler in order to run the Hamachi2. You should not run the Hamachi2 GUI on start-up because it is not necessary to connect the computer. Before the version 2.0.3.89, UPnP was working fine even with GUI client. So I think that it is a built-in bug which needs to be fixing quickly. The alternative way is "System" > "Preferences" > "Settings" > "Software Updates > Uncheck "Enable Automatic Update".
I have a Quick solution and that is you have to uninstall/remove version 2.0.3.89 and get the previous one which is of version 2.0.2.85. While removing, do no remove all the items of Hamachi. Also make sure to uncheck the Automatic Update. You can do the upgrade when you assume that there is a complete fix.
This may be due to your firewall or on your router. Anyway deputy must also ensure that Hamachi is given as a first network (otherwise may be out of order problems).
Have you enabled UPnP?
Or just your friends?
What NAT type do you have?