Windows Mail Error 0x800CCC0E

I can neither send nor receive mail from a newly set up account, here's the
error messages I get:

The connection to the server has failed. Subject 'Test Message.', Account:
'pop-server.xxxx.rr.com', Server: 'smtp-server.tampabay.rr.com', Protocol:
SMTP, Port: 25, Secure(SSL): No, Socket Error: 10061, Error Number: 0x800CCC0E

The connection to the server has failed. Account:
'pop-server.tampabay.rr.com', Server: 'pop-server.xxxx.rr.com', Protocol:
POP3, Port: 110, Secure(SSL): No, Socket Error: 10061, Error Number:
0x800CCC0E

According to the page at roadrunner, your POP and SMTP server names are
incorrect:
E-mail Server Addresses

"The outgoing (SMTP) mail server address is smtp-server.roadrunner.com.
The incoming (POP3) mail server address is pop-server.roadrunner.com."

pop-server.satx.rr.com is the POP3
smtp-server.satx.rr.com is the SMTP

you will do it this way and make it whatever your city and state is. EX:
pop-server.tampabay.rr.com is the POP3
smtp-server.tampabay.rr.com is the SMTP

IF YOU ALREADY DID IT THIS WAY, THEN YOU NEED TO FIND OUT FROM TWC IF THERE
IS A HYPHEN BETWEEN TAMPABAY OR NOT. YOU ARE PAYING FOR THEIR SERVICE, SO
TAKE ADVANTAGE OF CALLING THEM WHEN NECESSARY. THIS IS YOUR BEST BET.

[Vinata]

Check the smtp settings. Are you using your ISP's smtp settings or another such as yahoo or your own domain?

See this thread for more suggestions - Cannot send mail. Error 0x800CCC0E