I have a latest R835 from the Microsoft Store that has problem with my Microsoft wireless keyboard & mouse 3000. at times the mouse and keyboard work well, other times the cursor movement stutters, and sometimes, the keyboard and mouse stop operating completely, needing movement to a different USB port or a reboot. I exchanged in a wired mouse and it confirmed similar problem. So, I believe there is something going on with the USB ports or drivers - not certain how to test that. I contain all most recent updates for Windows 7 x64, in advantage all the up to date updates from the Toshiba site.
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